Effects of milk thistle on liver disease of alcohol, viral, toxin, cholestatic, and primary malignancy etiologies.

Milk thistle (Silybum marianum) has been used since Greco-Roman times as an herbal remedy for a variety of ailments, particularly liver problems. In the late 19th and early 20th centuries physicians in the United States used milk thistle seeds to relieve congestion of the liver, spleen, and kidneys. Today, several scientific studies suggest that active substances in milk thistle (particularly silymarin) protect the liver from damage caused by viruses, toxins, alcohol, and certain drugs such as acetaminophen (a common over the counter medication used for headaches and pain; acetaminophen, also called paracetamol, can cause liver damage if taken in large quantities or by people who drink alcohol regularly.)
Many professional herbalists recommend milk thistle extract for the prevention and/or treatment of various liver disorders including viral hepatitis, fatty liver associated with long term alcohol use, and liver damage from drugs and industrial toxins such as carbon tetrachloride.
Mushroom Poisoning
Milk thistle has also been used as a preventive and/or antidote to poisoning by deathcap mushroom (Amanita phalloides). Animal studies have found that milk thistle extract completely counteracts the toxic effects of the mushroom when given within 10 minutes of ingestion. If given within 24 hours of ingestion, the herb significantly reduces the risk of liver damage and death.
Liver disease from alcohol
A comprehensive review by the U.S. Agency for Healthcare Research and Quality (AHRQ) recently identified 16 scientific studies on the use of milk thistle for the treatment of various forms of liver disease. A European standardized extract of milk thistle was used in most of the trials.
Problems in study design (such as small numbers of participants, variations in the causes of liver disease, and differences in dosing and duration of milk thistle therapy) made it difficult to draw any definitive conclusions. However, five of seven studies evaluating milk thistle for alcoholic liver disease found significant improvements in liver function. Those with the mildest form of the disease appeared to improve the most. Milk thistle was less effective for those with severe liver disease such as cirrhosis. Cirrhosis is characterized by scarring and permanent, non-reversible damage to the liver. It is often referred to as end-stage liver disease.
Viral hepatitis
Despite the fact that milk thistle is widely used in the treatment of hepatitis (particularly hepatitis C), results from four viral hepatitis studies were contradictory. Some found improvements in liver enzyme activity while others failed to detect these benefits. None of the studies compared milk thistle with interferon or other medications for viral hepatitis.
Cancer
Preliminary laboratory studies also suggest that active substances in milk thistle may have anti-cancer effects. One active substance known as silymarin has strong antioxidant properties and has been shown to inhibit the growth of human prostate, breast, and cervical cancer cells in test tubes. Further studies are needed to determine whether milk thistle is safe or effective for people with these forms of cancer.
High cholesterol
One animal study found that silymarin (an active compound in milk thistle) worked as effectively as the cholesterol-lowering drug probucol, with the additional benefit of substantially increasing HDL ("good") cholesterol. Further studies in people are needed.

Milk Thistle protects and regenerates the liver in most liver diseases such as Cirrhosis (hardening of the Liver), Jaundice and Hepatitis, (inflammation of the Liver), and Cholangitis (inflammation of bile ducts resulting in decreased bile flow). It is one of the best examples of preventative medicine that we have today as it not only protects each cell of the liver from incoming toxins, but simultaneously encourages the liver to cleanse itself of damaging substances, such as alcohol, drugs, medications, mercury and heavy metals, pesticides, anesthesia, and even the most poisonous of mushrooms, the Amanita or Death-cap mushroom.
This herb is wonderful and appropriate for anyone who is under stress, uses alcohol, recreational drugs, prescription medications, or lives in today's modern times of pesticides, environmental toxins, and pollution? Virtually every person in an industrial nation.

Conclusions
Clinical efficacy of milk thistle is not clearly established. Interpretation of the evidence is hampered by poor study methods and/or poor quality of reporting in publications. Problems in study design include heterogeneity in etiology and extent of liver disease, small sample sizes, and variation in formulation, dosing, and duration of milk thistle therapy. Possible benefit has been shown most frequently, but not consistently, for improvement in aminotransferases and liver function tests are overwhelmingly the most common outcome measure studied. Survival and other clinical outcome measures have been studied least often, with both positive and negative findings. Available evidence is not sufficient to suggest whether milk thistle may be more effective for some liver diseases than others or if effectiveness might be related to duration of therapy or chronicity and severity of liver disease. Regarding adverse effects, little evidence is available regarding causality, but available evidence does suggest that milk thistle is associated with few, and generally minor, adverse effects.

This plant is native to the Mediterranean and grows wild throughout Europe, North America and Australia. Milk Thistle has been used in Europe as a remedy for liver problems for thousands of years. Its use was recorded in the first century (AD 23-79), noting that the plant was excellent for protecting the liver. Early Christian tradition dedicated milk thistle to Mary, calling it Marian thistle. In the 19th century the Eclectics used the herb for varicose veins, menstrual difficulty, and congestion in the liver, spleen and kidneys. Milk thistle has also been taken to increase breast-milk production, stimulate the secretion of bile, and as a treatment for depression and neutral milk hotel, milk, milk inc, breast milk, got milk, muscle milk, milk and cereal, milk shake, milk thistle, milk prices, evaporated milk substitute, milk sex, condensed milk fudge recipe, milk and milk product, benefit of soy milk, prairie milk, pregnant milk, carnation milk, milk thistle benefit, sweetened condensed milk recipe, skim milk, milk prostate, milk rap, powdered milk, westmoreland milk glass, whole milk, ass milk, selling breast milk, sweetened condensed milk, breast milk for sale, woman milk, milk bath, eagle brand milk, medication and mother milk.
Milk thistle nutritionally supports the liver's ability to maintain normal liver function. It has shown positive effects in treating nearly every known form of liver disease, including cirrhosis, hepatitis, necroses, and liver damage due to drug and alcohol abuse. Milk thistle works due to its ability to inhibit the factors responsible for liver damage, coupled with the fact it stimulates production of new liver cells to replace old damaged ones.
Milk thistle has been proven to protect the liver from damage. The detrimental effects of environmental toxins, alcohol, drugs and chemotherapy may be countered with this valuable herb. The active chemical component in the herb is silybin, which functions as an antioxidant and is one of the most potent liver protective agents known. Clinical trials have proven silybin to be effective in treating chronic liver diseases and in protecting the liver from toxic chemicals. An injection of silybin is a proven antidote for poisoning with the Deathcap mushroom (Amanita phalloides).
Silybin is a part of the chemical structure of the flavoligan silymarine. Milk thistle's hepatoprotective effects may be explained by its function of altering the liver cell membrane structure, blocking the absorption of toxins into the cells. Hepatoprotection by silymarin can also be attributed to its ability to increase the intracellular concentration of glutathione, a substance required for detoxicating reactions in liver cells. Milk thistle is also an antioxidant that is more potent than vitamins C and E.
Parts Used: Seeds for powdered or liquid extract.
Common Use: Helps the liver detoxification process. For all liver disorders such as jaundice and hepatitis. Fights pollutants and prevents free radical damage by action as antioxidant. Protects the liver and stimulates the production of new liver cells. Helps common skin conditions related to poor liver function.
Care: Annual or biennial tit milk, child festival milk toronto, raw milk, goat milk, soy milk, milk glass, mother milk, milk cow, chocolate milk, milk and cookie, milk my cock, milk maid, boob milk, milk of magnesia, organic milk, milk allergy, nuetral milk hotel, milk bottle, fat milk shake, soy milk maker, goat milk soap, neutral milk, milk carton, milk snake, milk and honey, the face on the milk carton, milk chocolate, milk junkie, milk money, silk soy milk, coconut milk, pigeon milk, harvey milk, milk frother, milk junkies, breast milk storage, milk man, milk sugar, baby milk, muscle milk review, milk steamer, rice milk, milk jug, evaporated milk, got milk ads, dead milk man, gallon of milk, milk jug skeleton, milk crate, milk squirting, milk delivery, cytosport muscle milk, condensed milk, milk paint, chocolate milk maid, medication medication milk milk mother mother, milk can, black milk, ichigo milk, milk powder, picture of milk, milk squirt, mother milk tea, milena velba milk, milk a to z, milk tea. Very drought tolerant, self seeds readily. Prefers sunny position and well drained, dry soil.

 

Got milk

Muscle milk

Breast milk

 

Web Hosting by Netfirms | Free Domain Names by Netfirms